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Chemistry and Biochemistry Labs
Peterson Lab

Publications

39. Terungwa Iorkula, Bryce Tolman, J. D. Singleton, and M. A. Peterson “An Efficient Microwave-Assisted Copper Catalyzed C-3 Amination of 3-Bromopyrazolo[1,5-a]pyrimidine” Tetrahedron Lett. 2023, 118, 154393

38. R. Dass, J. D. Singleton, and M. A. Peterson “An Efficient One-pot Synthesis of 4-Thiocyanato Anilines Using Benzyltrimethylammonium Dichloroiodate and Ammonium Thiocyanate in DMSO:H 2 O” Tetrahedron Lett. 2022, 98, 153809

37. R. Dass, and M. A. Peterson “An Efficient One-pot Synthesis of 2-Aminobenzothiazoles from Substituted Anilines Using Benzyltrimethylammonium Dichloroiodate and Ammonium Thiocyanate in DMSO:H 2 O” Tetrahedron Lett. 2021, 83, 153388

36. J. D. Singleton; R. Dass; N. R. Neubert; R. M. Smith, Z. Webber; M. D. H. Hansen; and M. A. Peterson “Synthesis and biological evaluation of novel pyrazolo[1,5-a]pyrimidines: Discovery of a selective inhibitor of JAK1 JH2 pseudokinase and VPS34. Bioorg. Med. Chem. Lett. 2020, 30, 126813.

35. P. Machicao; S. R. Burt, R. K. Christensen, N. B. Lohner, J. D. Singleton, and M. A. Peterson* “An efficient microwave assisted synthesis of N’-aryl/(alkyl)-substituted N-(4-hydroxy-6-phenylpyrimidin-2-yl)guanidines: Scope and limitations” Tetrahedron Lett. 2017, 58, 2318–2321

34. P. Machicao; M. A. Peterson,* and D. Schols “An efficient one-pot conversion of Boc-protected adenines to N6-ureas” Tetrahedron Lett. 2015, 56, 6574–6576.

33. J. R. Shelton, J. Balzarini, and M. A. Peterson* “Discovery of a nanomolar inhibitor of lung adenocarcinoma in vitro” Bioorg. Med. Chem. Lett. 2014, 24, 5107–5110.

32. J. R. Shelton and M. A. Peterson* “Efficient Synthesis of 5’-O-(N)-Carbamyl and Polycarbamyl Nucleosides” Tetrahedron Lett. 2013, 54, 6882–6885.

31. J. Balzarini, F. Gago, W. Kulik, A. B. P. van Kuilenburg, A. Karlsson, M. A. Peterson, and M. J. Robins “Introduction of a Fluorine Atom at C3 of 3-Deazauridine Shifts Its Antimetabolic Activity from Inhibition of CTP Synthetase to Inhibition of Orotidylate Decarboxylase, an Early Event in the de Novo Pyrimidine Nucleotide Biosynthesis Pathway” J. Biol. Chem. 2012, 287, 30444–30454.

30. J. R. Shelton, C. E. Cutler, M. S. Browning, J. Balzarini, and M. A. Peterson* “Synthesis and SAR of 2ʹ,3ʹ-bis-O-substituted- N 6 ,5'-bis-ureidoadenosine derivatives: Implications for prodrug delivery and mechanism of action.” Bioorg. Med. Chem. Lett. 2012, 22, 6067–6071.

29. J. R. Shelton, M. Oliveira, C. E. Cutler, J. Balzarini, and M. A. Peterson* "Synthesis, SAR, and preliminary mechanistic evaluation of novel antiproliferative N 6 ,5'-bis-ureido- and 5'-carbamoyl-N 6 -ureidoadenosine derivatives" Bioorg. Med. Chem. 2012, 20, 1008-1019.

28. J. R. Shelton, S. R. Burt, and M. A. Peterson* "A Broad Spectrum Anticancer Nucleoside with Selective Toxicity Against Human Colon Cancer Cells In Vitro," Bioorg. Med. Chem. Lett. 2011, 21, 1484–1487.

27. M. A. Peterson,* M. Oliveira, M. A. Christiansen, and C. E. Cutler “Preliminary SAR Analysis of Novel Antiproliferative N 6 ,5'-Bis-ureidoadenosine Derivatives” Bioorg. Med. Chem. Lett. 2009, 19, 6775–6779.

26. M. J. Robins,* H. Yang, K. Miranda, M. A. Peterson,* E. DeClercq, and J. Balzarini “Synthesis and Biological Evaluation of 3,3-Difluoropyridine-2,4(1H,3H)-dione and 3-Deaza-3-fluorouracil Base and Nucleoside Derivatives,” J. Med. Chem. 52, 3018–3027 (2009).

25. M. A. Peterson,* M. Oliveira, M. A. Christiansen “Antiproliferative and Protein Kinase Binding Activities of Some N 6 ,5'-Bis-ureido 5'-Amino-5'-deoxyadenosine Derivatives” Nucleos. Nucleot. Nucl. 28, 394–407 (2009).

24. M. J. Robins,* V. K., Rajwanshi, K. Miranda, M. A Peterson,* E. DeClercq, and J. Balzarini, "Synthesis and Antiviral Evaluation of 6-[Alkyl-heteroaryl)furo[2,3-d]pyrimidin-2(3H)-one Nucleosides and Analogues with Ethynyl, Ethenyl, and Ethyl Spacers at C6 of the Furopyrimidine Core" J. Med. Chem. 50, 3897–3905 (2007).

23. M. A. Peterson,* P. Ke, H. Shi, B. R. McDougal, and E. W. Robinson, Jr. "Design, Synthesis, and Antiviral Evaluation of Some 3'-Carboxymethyl-3'-deoxyadenosine Derivatives" Nucleos. Nucleot. Nucl. 26, 499–519 (2007).

22. M. A Peterson,* H. Shi, P. Ke "A Simple and Efficient Biphasic Method for the Preparation of 4-Nitrophenyl N-Methyl- and N-Alkylcarbamates" Tetrahedron Lett. 47, 3405–3407 (2006).

21. M. J. Robins,* K. Miranda, V. K. Rajwanshi, M. A Peterson,* G. Andrei, R. Snoeck, E. De Clercq, and J. Balzarini, "Synthesis and Biological Evaluation of 6-(Alkyn-1-yl) furo[2,3-d]pyrimidin-2(3H)-one Base and Nucleoside Derivatives" J. Med. Chem. 49, 391–398 (2006).

20. Z. Zhao, D. Gubler, J. Peacock, and M. A. Peterson,* "Photoinduced Bergman Cycloaromatization of Imidazole-Fused Enediynes" Tetrahedron Lett. 46, 1373–1375 (2005).

19. Z. Zhao, Y. Peng, N.K. Dalley, J.F. Cannon, and M.A. Peterson,* “Bergman Cycloaromatization of Imidazole-Fused Enediynes: The Remarkable Effect of N-Aryl Substitution,” Tetrahedron Lett., 45, 3621-3624 (2004).

18. M. A. Peterson,* A. Bowman, and S. Morgan, "Efficient Preparation of N-Benzyl Secondary Amines via Benzylamine–Borane Mediated Reductive Amination." Synthetic Commun. 32, 443-448 (2002).

17. E. S. Kumarasinghe, M. A. Peterson,* and M. J. Robins,* “Synthesis of 5, 6-bis (alkyn-1-yl) Pyrimidines and Related Nucleosides,” Tetrahedron Lett., 41, 8741-8745 (2000).

16. J. Z. Hu, M. S. Solum, R. A. Wind, B. L. Nilsson, and M. A. Peterson, " 1 H and 15 N Dynamic Nuclear Polarization Studies of Carbazole," J. Phys. Chem. A, 104, 4413-4420 (2000).

15. M.J. Robins,* B. Doboszewski, V.A. Timoshchuk and M.A. Peterson,* “Glucose-Derived 3'-(Carboxymethyl)-3'-deoxyribonucleosides and 2'-3'-Lactones as Synthetic Precursors for Amide-Linked Oligonucleotide Analogues,” J. Org. Chem., 65, 2939-2945 (2000).

14. M.J. Robins,* B. Doboszewski, B.L. Nilsson, and M. A. Peterson,* “Synthesis of Amide-Linked [(3')CH 2 CO-NH(5')] Nucleoside Analogues of Small Oligonucleotides,” Nucleosides, Nucleotides & Nucleic Acids, 19(1&2), 69-86 (2000).

13. M.A. Peterson* and B.L. Nilsson, “An Efficient Synthesis of ( 15 N)-Carbazole from ( 15 N)-Aniline,” Synthetic Commun., 29 (21), 3821-3827 (1999).

12. M.A. Peterson,* B.L. Nilsson, S. Sarker, B. Doboszewski, W. Zhang, and M.J. Robins,* “Amide-Lined Ribonucleoside Dimers Derived from 5'-Amino-5'-deoxy-and 3'-(Carboxymethyl)-3--deoxynucleoside Precursors,” J. Org. Chem., 64(22), 8183-8192 (1999).

11. M.A. Peterson* and J.R. Mitchell, “Efficient Preparation of 2-Bromo-6-lithiopyridine via Lithium-Bromine Exchange in Dichloromethane,” J. Org. Chem. 62, 8237-8239 (1997).

10. M.J. Robins,* S. Sarker, M. Xie, W. Zhang and M.A. Peterson,* “Synthesis of 2', 3'-Fused (3.3.0) γ-Butyrolactone-Nucleosides and Coupling with Amino Nucleosides to Give Amide-Linked Nucleotide-Dimer Analogues,” Tetrahedron Lett., 37, 3921-3924 (1996).

9. M.A. Peterson* and N. K. Dalley, “Highly Stereoselective Synthesis of a C 2 -Symmetric 2,2'-Bipyridine Derived from Glucose,” Synthetic Comm., 26(11), 2223-2228 (1996).

8. M.A. Peterson and R. Polt,* "N-Diphenylmethylene-Protected Glycosyl Acceptors. Selective -O-Glycosylation to Form Lactosyl-threo-Ceramides, "J. Org. Chem., 58, 4309, (1993).

7. R. Polt,* M.A. Peterson, and L. DeYoung, "Aluminoxy Acetals from -Amino Esters: Chirality Transfer via Sequential Addition of Hydrides and C-Nucleophiles. 2-Amino Alcohols and Sphingosines," J. Org. Chem., 57, 5469, (1992).

6. R. Polt* and M.A. Peterson, "E-1-Lithio-1-Alkenes in Hydrocarbon Solvent," Synthetic Comm., 22(3), 477, (1992).

5. R. Polt* and M.A. Peterson, "-Amino Alcohols from Amino Acids. Chelation Control via Schiff Bases," Tetrahedron Lett., 31, 4985, (1990).

4. M.E. Wright,* S.A. Svejda, M. Jin, and M.A. Peterson, "Bis(pyridyl)silane and -methanol Ligands. 3. A New Class of Optically Active Ligands Prepared from Readily Available Chiral 2-Bromo-6-Alkoxypyridines and Their Application in Rhodium-Catalyzed Hydrosilations and Copper (II)-Catalyzed Cyclopropanations," Organometallics, 9, 136, (1990).

3. C.T. Wittwer,* C.P. Graves, M.A. Peterson, E. Jorgensen, D. Wilson, J.G. Theone, B.W. Wyse, C.T. Windham, and R.G. Hansen, "Pantethine Lipomodulation: Mediation by Cysteamine in Vitro and in Vivo," Atherosclerosis, 68(1-2), 41, (1987).

2. M.A. Peterson, C.T. Wittwer,* E. Jorgensen, C.T. Windham, and B.W. Wyse, "The Effect of Pantothenate Status on Serum Triglycerides and Free Fatty Acids in Rats Fed a High Fat Diet," Federation of American Societies for Experimental Biology. Federation Proceedings, 46, 1489, (1987).

1. C.P. Graves, C.T. Wittwer,* M.A. Peterson, E. Jorgensen, C.T. Windham, B.W. Wyse and R.G. Hansen, "Pantethine Lipomodulation: Mediation by Cysteamine in Vitro and in Vivo," Federation of American Societies for Experimental Biology. Federation Proceedings, 46, 1476, (1987).