Ultrasensitive Biochemical Analysis
The Kelly lab focuses on developing methods, instrumentation and applications for in-depth bioanalyses of trace samples. Single-cell and high-resolution spatial proteomics are of particular interest. Current research efforts include:
- Simplifying and increasing efficiency of sample preparation for trace samples
- Miniaturizing separations for ultrasensitive measurements
- Developing LC instrumentation with no compromise between robustness, sensitivity and measurement throughput
- Alternative MS data acquisition strategies to get more information from trace samples
- Applications in cancer and neurodegenerative diseases