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Synthesis and evaluation of potent yaku'amide A analogs

May 02, 2022 12:41 PM
Concordia C. L. Lo, Daniel Joaquin, Diego A. Moyá, Alexander Ramos, David W. Kastner, Stephen M. White, Blake L. Christensen, Joseph G. Naglich, William J. Degnen, and Steven L. Castle

Towards a streamlined synthesis of peptides containing α,β-dehydroamino acids

September 03, 2021 08:41 PM
Diego A. Moyá, Michael A. Lee, Joseph C. Chanthakhoun, Austin K. LeSueur, Daniel Joaquin, Jaden D. Barfuss, Steven L. Castle

Synthesis of Functionalized Pyrrolines via Microwave-Promoted Iminyl Radical Cyclizations

September 03, 2021 08:30 PM
Jatinder Singh, Garrison A. Nickel, Yu Cai, Dakota D. Jones, Tanner J. Nelson, Jeshurun E. Small, and Steven L. Castle

Convergent Total Synthesis of Yaku'amide A

February 12, 2021 12:22 PM
Yu Cai, Zhiwei Ma, Jintao Jiang, Concordia C. L. Lo, Shi Luo, Ankur Jalan, Joseph M. Cardon, Alexander Ramos, Diego A. Moyá, Daniel Joaquin, Prof. Steven L. Castle

Impact of Dehydroamino Acids on the Structure and Stability of Incipient 310 Helical Peptides

July 30, 2020 05:26 PM
Daniel Joaquin, Michael A. Lee, David W. Kastner, Jatinder Singh, Shardon T. Morrill, Gracie Damstedt, and Steven L. Castle

Synthesis of Functionalized Nitriles by Microwave-Promoted Fragmentations of Cyclic Iminyl Radicals

July 30, 2020 05:25 PM
Mary M. Jackman, Siyeon Im, Seth R. Bohman, Concordia C. L. Lo, Amanda L. Garrity, Steven L. Castle

Bulky Dehydroamino Acids Enhance Proteolytic Stability and Folding in β-Hairpin Peptides

July 30, 2020 05:22 PM
Ankur Jalan, David W. Kastner, Kei G. I. Webber, Mason S. Smith, Joshua L. Price, and Steven L. Castle

Microwave-Promoted Tin-Free Iminyl Radical Cyclization with TEMPO Trapping: A Practical Synthesis of 2-Acylpyrroles

July 30, 2020 05:19 PM
Yu Cai, Ankur Jalan, Aaron R. Kubosumi, and Steven L. Castle

Total Synthesis of the Antimitotic Bicyclic Peptide Celogentin C

July 30, 2020 05:17 PM
Bing Ma, Biplab Banerjee, Dmitry N. Litvinov, Liwen He, and Steven L. Castle